Scintigraphic evaluation of brain death with 99mTc-d,l-hexamethyl-propyleneamine oxime(HMPAO).
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Evaluation of a new bombesin analogue labeled with 99mTc as potential targeted tumor scintigraphic agent
Background: Bombesin shows high affinity for Gastrin-releasing peptide (GRP) receptors which over expressed on the cell surfaces of several human tumors particularly in prostate and breast cancers. The aim of this study was labeling of designed analogue with99mTc via HYNIC and Tricine /EDDA and evaluation as potential targeted tumor scintigraphic agent. Materials and Methods: HYNIC-Bombesin wa...
متن کاملAssessment of antioxidative ability in brain: technetium-99m-meso-HMPAO as an imaging agent for glutathione localization.
UNLABELLED To visualize the regional localization of glutathione (GSH) in the brain, the relationship between the concentrations of tissue GSH and uptake of [99mTc]meso-hexamethyl propyleneamine oxime ([99mTc] meso-HMPAO) or [99mTc]d,l-hexamethyl propyleneamine oxime ([99mTc]d,l-HMPAO) was studied in mice. METHODS The uptake of [99mTc]meso-HMPAO in the mouse brain was decreased to 35% of cont...
متن کاملevaluation of a new bombesin analogue labeled with 99mtc as potential targeted tumor scintigraphic agent
background: bombesin shows high affinity for gastrin-releasing peptide (grp) receptors which over expressed on the cell surfaces of several human tumors particularly in prostate and breast cancers. the aim of this study was labeling of designed analogue with99mtc via hynic and tricine /edda and evaluation as potential targeted tumor scintigraphic agent.materials and methods: hynic-bombesin was ...
متن کاملEvaluation of Cardiac Function in Patients with Brain Death using Advanced Hemodynamic Monitoring
Background: Studies on hemodynamic changes in brain death are in vitro and in animal studies. And very few studies have been done on the hemodynamic changes of brain death. The aim of this study was to use advanced hemodynamic monitoring with echocardiography for evaluation of donated heart and to evaluate the moment by moment brain death patients with advanced hemodynamic monitoring tools and ...
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ژورنال
عنوان ژورنال: RADIOISOTOPES
سال: 1989
ISSN: 1884-4111,0033-8303
DOI: 10.3769/radioisotopes.38.8_335